VANESA is an open-source software project which aims to support scientist in the workflow of systems biology application cases. It provides a graphical user interface (GUI) and the general modeling approach is based on graphs. For Modeling, either biological networks or Petri nets can be chosen. Beside start modeling from scratch, a biological network can be retrieved from an data warehouse via web service.
Petri nets can be simulated with the help of an OpenModelica installation. Simulation results are made available for further investigation during process of simulation.
Both, biological networks as well as Petri nets, can be analyzed by general graph algorithms. Models are saved as SBML file, simulation results can be exported as CSV files, and graph pictures and charts can be saved as SVG, PNG and PDF files.
Unless simulation is desired, installation of Java SE 11+ and executing the provided jar file is sufficient. Simulation of Petri nets is based on OpenModelica. The latest compatible stable release should be used instead of nightly builds. The installation path must not contain any whitespaces! During installation process, make sure that you select PNlib as library to install. By default, all third party libraries will be installed. The installation process will also set some environment variables which are needed for VANESA to detect the OpenModelica installation.
If you used VANESA as part of your scientific work, please cite the following article:
C. Brinkrolf, C., S. J. Janowski, B. Kormeier, M. Lewinski, K. Hippe, D. Borck, R. Hofestädt VANESA - A Software Application for the Visualization and Analysis of Networks in Systems Biology Applications. Journal of Integrative Bioinformatics 11(2):239, 2014. DOI: 10.2390/biecoll-jib-2014-239
VANESA is an academic software project of the Bioinformatics / Medical Informatics Department of Faculty of Technology at Bielefeld University in Germany and its development started more than 10 years ago.